Goals
To
introduce students to the basic principles of pharmacology
·
Pharmacokinetics
·
Pharmacodynamics
To use our understanding of the basic
principles to describe the drug development process
Upon completion of this course students will be able
to
·
Distinguish between
pharmacokinetics and Pharmacodynamics.
·
Describe the different routes
of administration
·
Define absorption and identify
the relationship between administration, absorption and bioavailability
·
Describe the determinants of
distribution
·
Identify the primary sites of
drug metabolism
·
Describe the purpose of
metabolism and the processes involved
·
Describe the determinants of
drug metabolism
·
Identify the relationship
between drug metabolism and excretion
·
Describe the concept of steady
state concentration and what impacts it.
·
Define half life and the
kinetics of drug metabolism
·
Describe the impact of age on
all aspects of pharmacokinetics.
·
Describe the most common
mechanism of drugs action.
·
Identify the body control
systems
Receptors
Ion channels
Enzymes
Carrier molecules
·
Enumerate the types and
molecular structure of receptors.
·
Describe the chemistry of drug
receptor binding.
·
Define the dose response
relationship curves and their importance.
The course
will be in 3 modules each divided into 6 lectures and quizzes will be included in
each lecture.
Module one:
pharmacokinetics
Module two:
Pharmacodynamics
Module three:
drug development
In order to pass this course, you
must achieve a composite mark of at least 60 %
·
Attendance and daily quizzes
12%
·
Progress exam mcq 12%
·
Group assignment and
presentation 36%
·
End of session examination
short and long answer questions 40%
